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Receptor Screening Summary

Recently, as the therapeutic antibody development field has become active, it has been very important to identify the extracellular signaling target molecules participating receptor-ligand interaction for many diseases. And in the case of the target is ligand, it is necessary to identify the receptor to understand the exact mechanism of drug. Y-Biologics has more than 1,000 extracellular domains of human membrane proteins fused with Fc individually expressed by animal cell lines, followed by purification. Using this system, we established the analytical methods by ELISA for ligand-receptor binding.